WDR37

Predicted protein structure

Clinical relevance (Genomics England PanelApp)

Diagnostic Grade (Green)

• DDG2P

  MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown

• Early onset or syndromic epilepsy

  MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown

• Fetal anomalies

  MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted

• Intellectual disability

  MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown

• Severe microcephaly

  MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted

• Structural eye disease

  MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown

• Cerebellar hypoplasia

  MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted

Disease associations (Open Targets)

• neurooculocardiogenitourinary syndrome

  0.77

• coloboma

  0.47

• syndromic intellectual disability

  0.46

• hereditary disease

  0.45

• isolated cerebellar hypoplasia/agenesis

  0.39

• Intellectual disability

  0.38

• epilepsy

  0.38

• Peters anomaly

  0.37

• autism

  0.37

• Microcornea

  0.37

Score is the Open Targets composite evidence score (0-1). Higher = stronger gene-disease association.

Protein function (UniProt)

Diseases associated with WDR37

Curated MONDO disease pages that list WDR37 among their top associated genes.

• Peters anomalyRare