AlphaFold predicted structure
ZBTB11 · O95625
Mean pLDDT
61.1/ 100
Low
1,053 residues
Confidence breakdown
- Very high(≥ 90)1%
- Confident(70–90)48%
- Low(50–70)9%
- Very low(< 50)41%
Open interactive 3D viewer
AlphaFold (Jumper et al., 2021) · CC BY 4.0
ZBTB11
Chr 3q12.3zinc finger and BTB domain containing 11
- Aliases:
- ZNF-U69274, ZNF913
- MANE:
- ENST00000312938.5
Annotations refreshed 9 hours ago.
Predicted protein structure
Clinical relevance (Genomics England PanelApp)
Diagnostic Grade (Green)
DDG2P
BIALLELIC, autosomal or pseudoautosomalIntellectual disability
BIALLELIC, autosomal or pseudoautosomal
Disease associations (Open Targets)
intellectual developmental disorder, autosomal recessive 69
0.64autosomal recessive non-syndromic intellectual disability
0.46cancer
0.10neoplasm
0.09COVID-19
0.08lung cancer
0.07lung carcinoma
0.07breast cancer
0.07microcephaly
0.05multiple sclerosis
0.04
Score is the Open Targets composite evidence score (0-1). Higher = stronger gene-disease association.
Protein function (UniProt)
Zinc finger and BTB domain-containing protein 11
May be involved in transcriptional regulation