ZBTB24

Predicted protein structure

Clinical relevance (Genomics England PanelApp)

Diagnostic Grade (Green)

• COVID-19 research

  BIALLELIC, autosomal or pseudoautosomal

• Intellectual disability

  BIALLELIC, autosomal or pseudoautosomal

• Primary immunodeficiency or monogenic inflammatory bowel disease

  BIALLELIC, autosomal or pseudoautosomal

• Clefting

  BIALLELIC, autosomal or pseudoautosomal

• Fetal anomalies

  BIALLELIC, autosomal or pseudoautosomal

Disease associations (Open Targets)

• ICF syndrome

  0.79

• Intellectual disability

  0.37

• hereditary disease

  0.19

• Kabuki syndrome 1

  0.12

• clonal hematopoiesis

  0.08

• cardiac transplant

  0.07

• retinitis pigmentosa

  0.07

• Leber congenital amaurosis

  0.07

• Familial exudative vitreoretinopathy

  0.07

• Cone rod dystrophy

  0.06

Score is the Open Targets composite evidence score (0-1). Higher = stronger gene-disease association.

Protein function (UniProt)