AlphaFold predicted structure
ZBTB47 · Q9UFB7
Mean pLDDT
53.3/ 100
Low
747 residues
Confidence breakdown
- Very high(≥ 90)0%
- Confident(70–90)28%
- Low(50–70)19%
- Very low(< 50)53%
Open interactive 3D viewer
AlphaFold (Jumper et al., 2021) · CC BY 4.0
ZBTB47
Chr 3p22.1zinc finger and BTB domain containing 47
- Aliases:
- KIAA1190, DKFZp434N0615
- MANE:
- ENST00000232974.11
Annotations refreshed 9 hours ago.
Predicted protein structure
Clinical relevance (Genomics England PanelApp)
Diagnostic Grade (Green)
Early onset or syndromic epilepsy
MONOALLELIC, autosomal or pseudoautosomal, NOT imprintedIntellectual disability
MONOALLELIC, autosomal or pseudoautosomal, NOT imprintedDDG2P
MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown
Disease associations (Open Targets)
neurodevelopmental disorder
0.37neurodegenerative disease
0.24Seizure
0.12Neurodevelopmental delay
0.12pancreatic adenocarcinoma
0.03Global developmental delay
0.01Alzheimer disease
0.01digestive system carcinoma
0.00glioma
0.00central nervous system cancer
0.00
Score is the Open Targets composite evidence score (0-1). Higher = stronger gene-disease association.
Protein function (UniProt)
Zinc finger and BTB domain-containing protein 47
May be involved in transcriptional regulation