ZMYND11

Predicted protein structure

Clinical relevance (Genomics England PanelApp)

Diagnostic Grade (Green)

• DDG2P

  MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown

• Intellectual disability

  MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted

• Fetal anomalies

  MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted

Disease associations (Open Targets)

• intellectual disability, autosomal dominant 30

  0.66

• Intellectual disability

  0.59

• hereditary disease

  0.53

• smoking initiation

  0.38

• syndromic complex neurodevelopmental disorder

  0.37

• Global developmental delay

  0.34

• schizophrenia

  0.12

• neurodevelopmental disorder

  0.12

• Motor delay

  0.12

• Self-injurious behavior

  0.12

Score is the Open Targets composite evidence score (0-1). Higher = stronger gene-disease association.

Protein function (UniProt)