AlphaFold predicted structure
ZNF341 · Q9BYN7
Mean pLDDT
55.9/ 100
Low
854 residues
Confidence breakdown
- Very high(≥ 90)0%
- Confident(70–90)35%
- Low(50–70)14%
- Very low(< 50)50%
Open interactive 3D viewer
AlphaFold (Jumper et al., 2021) · CC BY 4.0
ZNF341
Chr 20q11.22zinc finger protein 341
- Aliases:
- dJ553F4.3
- MANE:
- ENST00000375200.6
Annotations refreshed 9 hours ago.
Predicted protein structure
Clinical relevance (Genomics England PanelApp)
Diagnostic Grade (Green)
COVID-19 research
BIALLELIC, autosomal or pseudoautosomalPrimary immunodeficiency or monogenic inflammatory bowel disease
BIALLELIC, autosomal or pseudoautosomal
Disease associations (Open Targets)
hyper-IgE recurrent infection syndrome 3, autosomal recessive
0.68neurodegenerative disease
0.54hyper-IgE syndrome
0.47skin neoplasm
0.40skin cancer
0.39actinic keratosis
0.39cutaneous melanoma
0.35skin disorder
0.33basal cell carcinoma
0.32Alzheimer disease
0.31
Score is the Open Targets composite evidence score (0-1). Higher = stronger gene-disease association.
Protein function (UniProt)
Zinc finger protein 341
Transcriptional activator of STAT3 involved in the regulation of immune homeostasis. Also able to activate STAT1 transcription