ZNF687

Predicted protein structure

Clinical relevance (Genomics England PanelApp)

Diagnostic Grade (Green)

• Skeletal dysplasia

  MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted

• Fetal anomalies

  MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted

Disease associations (Open Targets)

• bone Paget disease

  0.60

• ovarian dysfunction

  0.22

• hepatocellular carcinoma

  0.09

• neoplasm

  0.05

• granular cell tumor

  0.05

• cancer

  0.02

• lung adenocarcinoma

  0.02

• Paget disease

  0.02

• acute myeloid leukemia

  0.01

• colorectal carcinoma

  0.01

Score is the Open Targets composite evidence score (0-1). Higher = stronger gene-disease association.

Protein function (UniProt)