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hereditary spastic paraplegia

MONDO:0019064

Also known as: spastic paraplegia, HSP, SPG, Strümpell-Lorrain disease, familial spastic paraplegia

MONDO:
MONDO:0019064
Orphanet:
685
Rare disease91 associated genes

Description

Hereditary spastic paraplegias (HSP) comprise a genetically and clinically heterogeneous group of neurodegenerative disorders characterized by progressive spasticity and hyperreflexia of the lower limbs.

Associated genes

+81 more genes — install the extension to see the full list inline on any page.

External references

Sources: MONDO (CC BY 4.0), Open Targets (CC0), Orphanet (CC BY 4.0).

Not for sole clinical decision-making. Always verify against primary sources.