KRAS

Chr 12p12.1

KRAS proto-oncogene, GTPase

Aliases:: KRAS1, K-Ras4B
MANE:: ENST00000311936.8

OMIM: 190070 ↗NCBI: 3845 ↗Ensembl ↗

Predicted protein structure

AlphaFold predicted structure

KRAS · P01116

v62025-08-01

Predicted Aligned Error matrix for KRAS — diagonal shows residue index, colour shows pairwise prediction confidence (lower is better) — Predicted Aligned Error

Mean pLDDT

91.5/ 100

Very high

189 residues

Confidence breakdown

Very high(≥ 90)78%
Confident(70–90)15%
Low(50–70)5%
Very low(< 50)2%

Open interactive 3D viewer

AlphaFold (Jumper et al., 2021) · CC BY 4.0

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We have HGNC metadata for this gene, but the deeper annotations (ClinVar, gnomAD, PanelApp, …) populate when someone uses the GenoLens extension to look up this gene. Install the extension or check back in a moment.