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plasma cell myeloma

MONDO:0009693

Also known as: Kahler disease, Kahler's disease, Multiple Myeloma, medullary plasmacytoma, multiple myeloma, resistance to, Somatic mutation

MONDO:
MONDO:0009693
Orphanet:
29073
Rare disease161 associated genes

Description

A bone marrow-based plasma cell neoplasm characterized by a serum monoclonal protein and skeletal destruction with osteolytic lesions, pathological fractures, bone pain, hypercalcemia, and anemia. Clinical variants include non-secretory myeloma, smoldering myeloma, indolent myeloma, and plasma cell leukemia. (WHO, 2001)

Associated genes

+151 more genes — install the extension to see the full list inline on any page.

External references

Sources: MONDO (CC BY 4.0), Open Targets (CC0), Orphanet (CC BY 4.0).

Not for sole clinical decision-making. Always verify against primary sources.