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small cell lung carcinoma

MONDO:0008433

Also known as: SCLC, oat cell carcinoma, oat cell carcinoma (morphologic abnormality), poorly differentiated endocrine neoplasm, Small cell lung cancer

MONDO:
MONDO:0008433
Orphanet:
70573
Rare disease109 associated genes

Description

Small cell lung cancer (SCLC) is a highly aggressive malignant neoplasm, accounting for 10-15% of lung cancer cases, characterized byrapid growth, and early metastasis. SCLC usually manifests as a large hilar mass with bulky mediastinal lymphadenopathy presenting clinically with chest pain, persistent cough, dyspnea, wheezing, hoarseness, hemoptysis, loss of appetite, weight loss, and neurological and endocrine paraneoplastic syndromes. SCLC is primarily reported in elderly people with a history of long-term tobacco exposure.

Associated genes

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External references

Sources: MONDO (CC BY 4.0), Open Targets (CC0), Orphanet (CC BY 4.0).

Not for sole clinical decision-making. Always verify against primary sources.