hereditary breast ovarian cancer syndrome
MONDO:0003582Also known as: BRCA1- and BRCA2-associated hereditary breast and ovarian cancer (HBOC), Hereditary Breast and Ovarian Cancer Syndrome, familial breast and ovarian cancer syndrome, familial breast/ovarian cancer (BRCA1, BRCA2), hereditary breast and ovarian cancer
- MONDO:
- MONDO:0003582
- Orphanet:
- 145 ↗
Rare disease38 associated genes
Description
An autosomal dominant inherited syndrome caused by mutations in the BRCA1 or BRCA2 genes. Patients are at high risk of developing breast cancer, particularly before the age of fifty, high risk of developing a second primary breast cancer, and high risk of developing both breast and ovarian cancer.
Associated genes
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