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Townes-Brocks syndrome

MONDO:0007142

Also known as: TBS, Townes syndrome, Townes-Brocks syndrome, imperforate anus with hand, foot and ear anomalies, rear syndrome

MONDO:
MONDO:0007142
Orphanet:
857
Rare disease50 associated genes

Description

Townes-Brocks syndrome (TBS) is a rare genetic disorder characterized by the triad of imperforate anus, dysplastic ears often associated with sensorineural and/or conductive hearing impairment, and thumb malformations. These features are often associated with other signs mainly affecting the kidneys and heart.

Associated genes

+40 more genes — install the extension to see the full list inline on any page.

External references

Sources: MONDO (CC BY 4.0), Open Targets (CC0), Orphanet (CC BY 4.0).

Not for sole clinical decision-making. Always verify against primary sources.