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combined immunodeficiency

MONDO:0015131

Also known as: CID, congenital combined immunodeficiency, X-linked combined immunodeficiency

MONDO:
MONDO:0015131
Orphanet:
101972
Rare disease44 associated genes

Description

A broad classification of inherited disorders presenting at birth that affect both the cell-mediated and humoral aspects of the immune response. Circulating numbers of B lymphocytes, T lymphocytes and NK cells are variable but where present do not function properly. Susceptibility to infection is the primary concern.

Associated genes

+34 more genes — install the extension to see the full list inline on any page.

External references

Sources: MONDO (CC BY 4.0), Open Targets (CC0), Orphanet (CC BY 4.0).

Not for sole clinical decision-making. Always verify against primary sources.