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amyotrophic lateral sclerosis

MONDO:0004976

Also known as: ALS, Charcot disease, Lou Gehrig disease, amyotrophic lateral sclerosis

MONDO:
MONDO:0004976
Orphanet:
803
Rare disease149 associated genes

Description

Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease characterized by progressive muscular paralysis reflecting degeneration of motor neurons in the primary motor cortex, corticospinal tracts, brainstem and spinal cord.

Associated genes

+139 more genes — install the extension to see the full list inline on any page.

External references

Sources: MONDO (CC BY 4.0), Open Targets (CC0), Orphanet (CC BY 4.0).

Not for sole clinical decision-making. Always verify against primary sources.